梁连铭 副研究员，硕士生导师
Email：lianglm@ynu.edu.cn
个人简介：
梁连铭，博士，副研究员，硕士生导师。云南省中青年学术和技术带头人、云南省万人计划青年拔尖人才。中国菌物学会菌物遗传及分子专业委员会委员。
课题组主要围绕食线虫真菌侵染线虫的分子机制并利用食线虫真菌进行农作物病原线虫生物防治展开研究工作。主持国家自然科学基金项目5项，省基金重点项目1项，面上项目2项。在Phil. Trans. R. Soc. B，Microbiology Spectrum, FASEB Journal，Journal of Fungi，Applied Microbiology and Biotechnology，Fungal Genetics and Biology等国际知名期刊上发表论文30余篇。第一作者参编专著4部。授权国家发明专利4项。
招生专业：
微生物学硕士
生物与医药——微生物学方向
研究方向：
通过基因组学，转录组学，生物信息学及功能基因等方法重点开展以下几方面的研究：
1. 捕食线虫真菌指状德氏霉产收缩环及捕虫机制研究；
2. 植物病害生物防治研究。
代表性研究成果：
1. Zhang, L., Zhang, T., Xu, Y.-R., Sun, J.-M., Pan, X.-R., Gu, K.-Z., . . . Liang, L.-M. (2025). "Induction of conidial traps in the nematode-trapping fungus Drechslerella dactyloides by soil microbes." mSystems, 10(3), e0129124.
2. Wei, Y., F.-N. Qi, Y.-R. Xu, K.-Q. Zhang, J. Xu, Y.-R. Cao and L.-M. Liang* (2024). "Characterization of regulatory genes Plhffp and Plpif1 involved in conidiation regulation in Purpureocillium lavendulum." Frontiers in Microbiology 15: 1352989.
3. Li, X.(†), L.-M. Liang(†), Z.-B. Hua, X.-K. Zhou, Y. Huang, J.-H. Zhou, Y. Cao, J.-J. Liu, T. Liu and M.-H. Mo (2024). "Eco-friendly management of Meloidogyne incognita in cadmium-contaminated soil by using nematophagous fungus Purpureocillium lavendulum YMF1.683: Efficacy and mechanism." Environmental Research. 244: 117930.(†并列第一作者)
4. Zhuang, X.-M., Z.-Y. Guo, M. Zhang, Y.-H. Chen, F.-N. Qi, R.-Q. Wang, L. Zhang, P.-J. Zhao, C.-J. Lu, C.-G. Zou, Y.-C. Ma, J. Xu, K.-Q. Zhang, Y.-R. Cao and L.-M. Liang* (2023). "Ethanol mediates the interaction between Caenorhabditis elegans and the nematophagous fungus Purpureocillium lavendulum. Microbiology Spectrum. 11(5): e01270-01223.
5. Tang, P., J.-J. Han, C.-C. Zhang, P.-P. Tang, F.-N. Qi, K.-Q. Zhang and L.-M. Liang* (2023). The Growth and Conidiation of Purpureocillium lavendulum Are Co-Regulated by Nitrogen Sources and Histone H3K14 Acetylation. Journal of Fungi. 9(3): 325.
6. Chen, M., H.-Y. Yang, Y.-R. Cao, Q.-Q. Hui, H.-F. Fan, C.-C. Zhang, J.-J. Han, Z.-Y. Guo, J. Xu, K.-Q. Zhang, et al. (2020). Functional Characterization of Core Regulatory Genes Involved in Sporulation of the Nematophagous Fungus Purpureocillium lavendulum. mSphere. 5(5): e00932-00920.
7. Liang, L. M., C. G. Zou, J. Xu and K. Q. Zhang (2019). Signal pathways involved in microbe-nematode interactions provide new insights into the biocontrol of plant-parasitic nematodes. Philos Trans R Soc Lond B Biol Sci. 374(1767): 20180317.
8. Liu, L., Y.-R. Cao, C.-C. Zhang, H.-F. Fan, Z.-Y. Guo, H.-Y. Yang, M. Chen, J.-J. Han, J. Xu, K.-Q. Zhang, and L.-M. Liang*. (2019). An Efficient Gene Disruption System for the Nematophagous Fungus Purpureocillium lavendulum. Fungal Biology. 123(4): 274-282.
9. Liang, L., Z. Liu, L. Liu, J. Li, H. Gao, J. Yang and K. Q. Zhang (2016). The nitrate assimilation pathway is involved in the trap formation of Arthrobotrys oligospora, a nematode-trapping fungus. Fungal Genetics & Biology. 92: 33-39.
10. Liang, L., R. Shen, Y. Mo, J. Yang, X. Ji and K.-Q. Zhang (2015). A proposed adhesin AoMad1 helps nematode-trapping fungus Arthrobotrys oligospora recognizing host signals for life-style switching. Fungal Genetics and Biology. 81: 172-181.
11. Liang, L., S. Liu, J. Yang, Z. Meng, L. Lei and K. Zhang (2011). Comparison of homology models and crystal structures of cuticle-degrading proteases from nematophagous fungi: structural basis of nematicidal activity. FASEB J. 25(6): 1894-1902.
12. Liang, L., Z. Meng, F. Ye, J. Yang, S. Liu, Y. Sun, Y. Guo, Q. Mi, X. Huang, C. Zou, et al. (2010). The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes. FASEB J. 24(5): 1391-1400.
