李一青 硕士生导师
Email：yiqingli@ynu.edu.cn
个人简介：
李一青，博士，研究员，英国365公司官网、西南微生物多样性教育部重点实验室。
主要从事微生物活性天然产物研究，主持完成国家自然科学基金4项，先后赴德国HKI天然产物研究所及韩国建国大学进行合作研究，在Journal of Agricultural and Food Chemistry, Organic & Biomolecular Chemistry, Microbial Biotechnology, Journal of Antibiotics等国际刊物发表SCI论文20余篇，以第一发明人获得授权发明专利10项。
招生专业：
微生物学
研究方向：
1.微生物药物资源的收集及活性筛选。
2. 微生物医药、农药活性先导新化合物的发现。
代表性研究成果：
1. X. D. Xu, Y. Zhao, K. Bao, C. P. Miao, S. K. Tang, S. H. Wu, Y. Q. Li. Isolation, structure elucidation and antifungal activity of angucycline antibiotics from Streptomycete cellulosae. Applied Biochemistry and Microbiology, 2023, 59 (4): 456-461.
2. Xiao Chen, Qin-Yuan Li, Yang Zhao, Cui-Ping Miao, Li-Xing Zhao, Cheng-lin Jiang, Shao-Hua Wu, Yi-Qing Li. Migrastatin, iso-migrastatin and their analogues isolated from Streptomycete ardus. Chemistry of Natural Compounds, 2023, 59 (5): 900-902.
3. Xindong Xu, Yang Zhao, Kang Bao, Cuiping Miao, Lixing Zhao, Youwei Chen, Shaohua Wu, Yiqing Li. Purification and characterization of anti-phytopathogenic fungi angucyclinone from soil‑derived Streptomyces cellulosae. Folia Microbiologica, 2022, 67, 517-522.
4. Junli Dong, Beibei He, Zhou Jiang, Ruinan Wang, Xiuli Zuo, Rui Zhan, Linfang Hu, Yiqing Li, Jing He. Characterization of the diastaphenazine/izumiphenazine C biosynthetic gene cluster from plant endophyte Streptomyces diastaticus W2. Microbial Biotechnology, 2022, 15(4): 1168-1177.
5. Xiao Chen, Jinmei Zou, Lei Li, Kang Bao, Yang Zhao, Cuiping Miao, Lixing Zhao, Youwei Chen, Yiqing Li. Cyclic peptide secondary metabolites with antifungal activity against root-rot pathogens of Panax Notoginseng produceded by Streptomyces yatensis. Chemistry of Natural Compounds, 2021, 57 (6): 1181-1183.
6. Xiao Chen, Linfang Hu, Xueshi Huang, Lixing Zhao, Cuiping Miao, Youwei Chen, Lihua Xu, Li Han, Yiqing Li. Isolation and characterization of new phenazine metabolites with antifungal activity against root-rot pathogens of Panax Notoginseng from Streptomyces. Journal of Agricultural and Food Chemistry, 2019, 67, 11403-11407.
7. Linfang Hu, Xiao Chen, Li Han, Lixing Zhao, Cuiping Miao, Xueshi Huang, Youwei Chen, Ping Li, Yiqing Li. Two new phenazine metabolites with antimicrobial activities from soil-derived Streptomyces species. Journal of Antibiotics, 2019 72(3): 574-577.
8. Xindong Xu, Li Han, Lixing Zhao, Xiao Chen, Cuiping Miao, Linfang Hu, Xueshi Huang, Youwei Chen, Yiqing Li. Echinosporin antibiotics isolated from Amycolatopsis strain and their antifungal activity against root-rot pathogens of the Panax notoginseng. Folia Microbiologica, 2019, 64 (2), 171-175.
9. Yiqing Li, Li Han, He Rong, Liya Li, Lixing Zhao, Longxia Wu, Lihua Xu, Yi Jiang, Xueshi Huang. Diastaphenazine, a new dimeric phenazine from an endophytic Streptomyces diastaticus subsp. Ardesiacus. Journal of Antibiotics, 2015, 68(3): 210-212.
10. Dan Zheng, Li Han, Yiqing Li, Jun Li, He Rong, Qiao Leng, Yi Jiang, Lixing Zhao, Xueshi Huang. Isostreptazolin and sannaphenol, two new metabolites from Streptomyces sannanensis. Molecules, 2012, 17(1): 836-842.
11. Yiqing Li, Dan Zheng, Jun Li, Li Han, Xiaolong Cui, Li Lang, Minggang Li, Zhanyou Wang, Jiangyuan Zhao, Xueshi Huang. Sannanine, a new cytotoxic alkaloid from Streptomyces sannanensis. Journal of Antibiotics. 2009, 62(11): 647-648.
12. Yiqing Li, Xueshi Huang, Keishi Ishida, Armin Maier, Gerhard Kelter, Yi Jiang, Gundela Peschel, Klausdieter Menzel, Minggang Li, Mengliang Wen, Lihua Xu, Susanne Grabley, Heinzherbert Fiebig, Chenglin Jiang, Christian Hertweck and Isabel Sattler: Plasticity in gilvocarcin-type C-glycoside pathways: discovery and antitumoral evaluation of polycarcin V from Streptomyces polyformus. Organic & Biomolecular Chemistry. 2008, 19(6): 3601-3605.
13. Yiqing Li, Minggang Li, Wei Li, Jiangyuan Zhao, Zhanggui Ding, Xiaolong Cui, Mengliang Wen. Griseusin D, a New pyranonaphthoquinone derivative from a alkaphilic Nocardiopsis sp.. Journal of Antibiotics. 2007, 60(12): 757-761.
