赵沛基，博士生导师
云南省中青年学术和技术带头。
Email：pjzhao@ynu.edu.cn
个人简介：
赵沛基，英国365公司官网，博士，研究员，博士生导师，云南省中青年学术技术带头人。主要聚焦微生物致病机制、亚细胞结构和生物农药创制领域，研究内容包括微生物生防资源发掘及致病机制解析、亚细胞结构的研究，及产品创制开发与田间应用技术集成。以第一或通讯作者发表SCI源刊论文50余篇，获授权专利5件。
招生专业：
微生物博士、硕士
生物与医药——微生物学方向
研究方向：
主要从事微生物生理生化和生理代谢的研究。重点开展以下研究：
1、 研究方向活性天然产物的发现、生物合成及其功能的研究
2、 微生物细胞结构及其细胞器功能的研究
代表性研究成果：
1. Xing-Fu Wen, Ting-Ting Shi,Ya-Qi Zhang, Si-Han Wang, Chun-Mei Xiang, Pei-Ji Zhao*. DHXT1, a Virulence Factor of Dactylellina haptotyla, Regulates Pathogenicity by Participating in Trap Formation and Metabolite Synthesis. International Journal of Molecular Sciences, 2024, 25(13), 7384.
2. Min Chen, Ying Huang, Li Ma, Jian-Jin Liu, Yi Cao, Pei-Ji Zhao*, Ming-He Mo*. Cis-3-Indoleacrylic Acid: A Nematicidal Compound from Streptomyces youssoufiensis YMF3.862 as V-ATPase Inhibitor on Meloidogyne incognita. Journal of Agricultural and Food Chemistry, 2024, 72, 44, 24347-24358.
3. Hong-Mei Lei, Wang, Jun-Tao, Qian-Yi Hu, Chun-Qiang Li, Ming-He Mo, Ke-Qin Zhang, Guo-Hong Li, Pei-Ji Zhao*. 2-Furoic acid associated with the infection of nematodes by Dactylellina haptotyla and its biocontrol potential on plant root-knot nematodes. Microbiology Spectrum, 2023, 11(5): e0189623.
4. Qian-Yi Hu, Xue-Juan Pu, Guo-Hong Li, Chun-Qiang Li, Hong-Mei Lei, Ke-Qin Zhang, Pei-Ji Zhao*. Identification and mechanism of action of the global secondary metabolism regulator SaraC in Stereum hirsutum. Microbiology Spectrum, 2022, 10(6): e0262422.
5. Chun-Qiang Li, Hong-Mei Lei, Qian-Yi Hu, Guo-Hong Li, Pei-Ji Zhao*. Recent advances in the synthetic biology of natural drugs. Frontiers in Bioengineering and Biotechnology, 2021, 9:691152.
6. Xue-Juan Pu, Qian-Yi Hu, Su-Su Li, Guo-Hong Li, Pei-Ji Zhao*. Sesquiterpenoids and their quaternary ammonium hybrids from the mycelium of mushroom Stereum hirsutum by medium optimization. Phytochemistry, 2021, 189:112852.
7. Na Bai, Guo-Hong Li, Shao-Liu Luo, Liangcheng Du, Qian-Yi Hu, Han-Ke Xu, Ke-Qin Zhang*, Pei-Ji Zhao*. Vib-PT, an aromatic prenyltransferase involved in the biosynthesis of vibralactone from Stereum vibrans. Applied and Environmental Microbiology. 2020, 86 (10): e02687-19.
8. Yin-He Yang, Da-Song Yang, Guo-Hong Li, Xue-Juan Pu, Ming-He Mo, Pei-Ji Zhao*. Antibacterial diketopiperazines from an endophytic fungus Bionectria sp. Y1085. The Journal of Antibiotics, 2019, 72, 752-758.
9. Yuan-Chang Duan, Jun Feng, Na Bai, Guo-Hong Li, Ke-Qin Zhang,* Pei-Ji Zhao* Four novel antibacterial sesquiterpene-α-amino acid quaternary ammonium hybrids from the mycelium of mushroom Stereum hirsutum. Fitoterapia, 2018, 128: 213-217.
10. Jing Li, Jin Xie, Yin-He Yang, Xiao-Lian Li, Ying Zeng, Pei-Ji Zhao*. Pestalpolyols A–D, cytotoxic polyketides from Pestalotiopsis sp. cr013. Planta Medica, 2015, 81: 1285-1289.
11. Pei-Ji Zhao*, Yan-Long Yang, Liangchen Du, Ji-Kai Liu, Ying Zeng*. Elucidating the biosynthetic pathway for vibralactone, a novel pancreatic lipase inhibitor with a fused bicyclic β-lactone. Angewandte Chemie - International Edition, 2013, 52 (8): 2298-2302.
12. Yin-He Yang, Xiao-Li Fu, Liang-Qun Li, Ying Zeng, Cheng-Yun Li, Yi-Neng He, Pei-Ji Zhao*. Naphthomycins L−N, Ansamycin Antibiotics from Streptomyces sp. CS. Journal of Natural Products, 2012, 75, 1409-1413.
授权专利
1. 赵沛基, 包正雪, 李国红, 莫明和, 张克勤。 吡咯-2-甲醛在防治植物根结线虫中的应用； 专利号：ZL 2022 1 0540356.9;授权日期2023,04,28.
2. 赵沛基, 蒲雪娟, 王婷, 张克勤. 一种胶状溶杆菌发酵液的制备方法及应用. 专利号：ZL 201910649571.0;授权时间: 2022,11,11
3. 赵沛基, 雷红梅, 莫明和, 李国红, 张克勤. 一种含呋喃类化合物的杀虫剂及其应用. 专利号：ZL 202010512960.1. 授权时间: 2021,07,01
4. 赵沛基, 柳成莽, 张克勤, 李国红. 一种真菌拟盘多毛孢提取物及其应用.专利号：ZL 2017 1 0265010.1. 授权时间: 2019,8,23.
5. 赵沛基, 李靖, 谢津. 具有抗细菌活性的Pestalotic acid化合物及其应用. 专利号：ZL 2015 1 0955816.4. 授权时间: 2019,08,13.
